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Manufacturing Partners / Processing Logic

Processing logic for DermisIQ treatment architectures.

This overview outlines the conceptual processing logic IQ Labs LLC uses when designing DermisIQ treatment architectures. It is not a prescriptive formula or full manufacturing instruction. Instead, it is intended to help partners understand how we think about phase structure, thermal handling, and emulsification flow so that development work can align more quickly with our expectations.

Phase architecture at a glance

DermisIQ treatment systems are generally organized into six conceptual phases (A–F), separating water structuring, oil/emollient systems, emulsifiers, actives, and encapsulated materials. The exact implementation will vary by manufacturer and chosen base, but this structure helps support texture control, stability, and predictable scale-up.

  • • Phases A–B: Core water and oil/structuring systems
  • • Phase C: Emulsification and build structure
  • • Phase D: Heat-sensitive and post-emulsification inputs
  • • Phase E: Encapsulated systems and specialty components
  • • Phase F: Fragrance, final adjustments, and line-aligned modifications

Final processing parameters, order of addition, and specific tolerances are always adjusted to align with each manufacturer's equipment, SOPs, and safety practices.

Phase A — Water & hydration system

Phase A typically contains the primary aqueous phase and hydrating backbone. This may include humectants, water structuring agents, and pH-adjusting components as appropriate.

  • • Base water, humectants, and compatible solubilized inputs
  • • Early pH targeting where helpful for downstream phases
  • • Consideration of shear and hydration time where relevant

Phase B — Oils, emollients & structural lipids

Phase B is generally composed of the oil phase and structural lipid system. This is where we control slip, occlusivity, and base sensorial characteristics.

  • • Emollients aligned with the target soft-matte finish
  • • Structural lipids and waxes, as concept requires
  • • Thermal handling chosen to match manufacturer equipment

Phase C — Emulsifiers & structure-build

Phase C focuses on bringing Phases A and B together to form a stable emulsion. Emulsifiers, rheology modifiers, and select stabilizers are balanced to support the target viscosity and finish.

  • • Primary emulsifier systems and co-emulsifiers
  • • Rheology/structure modifiers appropriate for scale
  • • Alignment with shear, mixing time, and temperature profile

Phase D — Heat-sensitive actives & refinements

Once the main emulsion is established and cooled within the manufacturer's target window, Phase D typically incorporates heat-sensitive actives and refinement agents.

  • • Sensitive actives best added post-emulsification
  • • Additional sensorial refiners as needed
  • • Adjustments guided by lab stability and pilot data

Phase E — Encapsulated systems & specialty components

For concepts utilizing encapsulated or time-modulated systems (such as nano-liposomal niacinamide), Phase E is reserved to help preserve integrity while integrating smoothly into the emulsion.

  • • Incorporation at temperatures and shear rates appropriate to the delivery system
  • • Consideration of charge, pH, and compatibility with the base
  • • Documentation of any special handling requirements identified during R&D

Phase F — Fragrance, checks & line alignment

Phase F typically includes fragrance (if used), preservative system finalization, and last-mile adjustments tied to line compatibility and packaging performance.

  • • Addition of fragrance or aroma profile where applicable
  • • Final pH, viscosity, and appearance verification against agreed ranges
  • • Alignment on fill temperature and hold behavior for the selected filling line

Adapting the framework to each facility.

This phase structure is intended as a conceptual map rather than a fixed formula. IQ Labs LLC recognizes that each manufacturing partner has unique equipment, preferred processing sequences, and SOPs. We are flexible in adapting this logic to fit within your established workflows while preserving the texture, stability, and performance profile that define DermisIQ.

Detailed order of addition, specific temperatures, and mixing parameters are confirmed collaboratively during R&D and pilot work, and are not published externally. This page is provided solely to support early technical alignment and efficient evaluation of project fit.